Template Activity of Modified Terminator Codons
نویسندگان
چکیده
منابع مشابه
Template activity of modified terminator codons.
Modified trinucleotides, 3MeU-A-G+, 3MeU-A-A, 5MeUA-G, 5MeU-A-A, BrU-A-G, hU-A-G, and U-A-I (see J. BioZ. Chem., 241, 527 (1966)), were synthesized by a combination of organic and enzymatic methods. The activity of each trinucleotide as a template for peptide chain termination was determined. The attachment of a methyl group to the NB position of uracil eliminates the template activity of termi...
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Terminator
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About one-half of the terminators of the Escherichia coli genome require transcription termination factor rho to function. Here we use the very "diffuse" trp t' terminator of E. coli to show that both template sequence and transcript secondary structure are involved in controlling the template positions and efficiencies of rho-dependent termination. Termination begins in the wild-type trp t' te...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1970
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)63132-1